Article History
Received: 22 May 2018
Accepted: 26 July 2018
First Online: 6 August 2018
Ethics approval and consent to participate
: Not applicable.
: Not applicable.
: The authors are either directly or indirectly affiliated to Ophiuchus Medicine. Y.H. and S.O. are officers and shareholders of Ophiuchus Medicine. H.G.’s AscentGene is a subcontractor of Ophiuchus Medicine. This work was funded by Ophiuchus Medicine which owns the rights to the patents pending of the fusion proteins described in this study. The entire study was done at the request of, by and for Ophiuchus Medicine. The funding body participated in the design, optimization and data generation of the fusion proteins and linkers in silico and for analyzing the generated data. The funding body participated in conception, design and data analysis regarding the protein production and purification system and protein inhibition assays and antiviral assays. The funding body participated in writing the manuscript.
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