Gargiulo, Piera
Arenare, Laura
Gridelli, Cesare
Morabito, Alessandro
Ciardiello, Fortunato
Gebbia, Vittorio
Maione, Paolo
Spagnuolo, Alessia
Palumbo, Giuliano
Esposito, Giovanna
Della Corte, Carminia Maria
Morgillo, Floriana
Mancuso, Gianfranco
Di Liello, Raimondo
Gravina, Adriano
Schettino, Clorinda
Di Maio, Massimo
Gallo, Ciro
Perrone, Francesco
Piccirillo, Maria Carmela
Article History
Received: 20 February 2021
Accepted: 6 May 2021
First Online: 14 May 2021
Declarations
:
: Primary results of the 6 randomized trials have already been published, and all of them were approved by the Independent Ethics Committee of National Cancer Institute of Naples and by the Ethics Committee of each participating Institution. All patients gave written informed consent. The trials were conducted according to the Good Clinical Practice and Declaration of Helsinki.
: Not applicable.
: PG, LA, AS, PM, GP, GE, GM, RDL, CS, CG declare that they have no competing interests.CG reports personal fees from BMS, AstraZeneca, Roche, MSD and Menarini; fees for Speaker and Advisory Boards from BMS, AstraZeneca, Roche, MSD; fees for Consultant from Roche and Menarini, fees for Advisory Boards from Novartis and Amgen, outside the submitted work.AM reports personal fees from Roche, MSD, Pfizer, BMS, Takeda, AstraZeneca, Boehringer, Eli-Lilly, outside the submitted work.FC reports fees for Advisory Boards from Amgen, Merck, Pfizer, Sanofi, Bayer, Servier, BMS, Celgene, Eli-Lilly, Roche and Institutional Research Grants from Amgen, Merck, Bayer, AstraZeneca, Ipsen, Roche, outside the submitted work.VG reports fees for Speaker from Eli-Lilly, outside the submitted work.CMDC reports fees for Advisory Boards from MSD, outside the submitted work.FM reports fees for Advosory Boards from MSD and Eli-Lilly, Institutional Reaserch Grants from AstraZeneca, outside the submitted work.AG reports non-financial support from Pfizer, outside the submitted work.MDM reports Institutional Research grants from Tesaro-GlaxoSmithKline, fees for Consultant from AstraZeneca, Pfizer, Roche, Novartis, Takeda, Merck Sharp & Dohme; fees for Advisory Board from Janssen-Cilag, Astellas and Eisai, outside the submitted work.FP reports personal fees from Bayer, Ipsen, AstraZeneca, Bristol Myers Squibb, Sandoz, Incyte, Celgene, Pierre Fabre, Janssen-Cilag, outside the submitted work.MCP reports fees for Consultant from Daichii Sankyo, GlaxoSmithKline, MSD, AstraZeneca, Research grants from Roche, AstraZeneca and Non-financial support from Bayer, outside the submitted work<b>.</b>