Agizew, Tefera B.
Soka, Joseph
Fast, Cynthia D.
Mwimanzi, Stephen
Mwesiga, Gilbert
Edward, Nashon
Stephen, Marygiven
Kondo, Reheme
Burny, Robert
Cox, Christophe
Beyene, Negussie
Article History
Received: 29 September 2023
Accepted: 10 April 2024
First Online: 15 April 2024
Declarations
:
: The study protocol was approved by the Institutional Review Board (<i>IRB, Ref. nr. NMRI/HQ/R.8c/Vov.I/2066</i>) at the Tanzanian National Institute for Medical Research (Dar es Salaam, Tanzania). Following IRB approval, patients were enrolled in the study, and data were collected as part of the national TB program’s routine TB diagnostic care activities. Therefore, the ethical committee waived the need for informed consent for this operational research that involved second-line TB screening following routine care.Pertaining to the rats, all procedures were conducted with approval from the Institutional Committee for Research Involving Animals of the Sokoine University of Agriculture and in accordance with all relevant guidelines and regulations. The methods and results reported herein adhere to the National Centre for Replacement Refinement & Reduction of Animals in Research ARRIVE 2.0 guidelines. At the conclusion of all experiments, subjects remained housed according to the procedures described above with no animals sacrificed.
: Not applicable.
: The authors declare no competing interests.